Enzalutamide

What Is Enzalutamide?

Enzalutamide is the preferred prescription medicine that is used for treating prostate cancer in men.

The medicine is prescribed for men who receive hormone therapy or surgery for lowering testosterone.

The enzalutamide is also widely used if the cancer treatment is no longer responding. The enzalutamide is also widely helpful for avoiding the spread of cancer cells in the body.

The effect of enzalutamide is not safe for females and women. Xtandi is normally the androgen receptor inhibitor, which is useful for treating prostate cancers.

The xtandi works by easily preventing the action of the Androgens or male hormones.

 These are the best medicines when prostate cancer is no longer responding to surgical treatment or hormone therapy.

Xtandi is also a suitable option for avoiding the spread of cancer cells to other parts of the body.

These are significant options for controlling cancer cell growth along with decreasing the Tumour size. Knowing the xtandi uses before taking the medication is quite helpful.

Xtandi is used for patients with having high risk of cancer spreading to other parts of the body. Normally, the Xtandi is the most commonly used FDA-approved medicine.

How Does Enzalutamide Work?

Enzalutamide is the Androgen Receptor (AR) inhibitor to easily make the complete Castration-Resistant Prostate Cancer (CRPC) treatments.

 These involve both the metastatic and non-metastatic.

 Normally, xtandi involves the second-generation antiandrogen agent, which is widely approved by the FDA.

The Androgen Deprivation Therapy (ADT) are also involved with first-line treatment for treating prostate cancer. It also involves the remission achieved along with raising the resistance.

ADT is also one of the treatments for castration-resistant prostate cancer.

AR inhibitors were developed for targeted therapy, and it is first-generation AR inhibitors.

 Prostate cancers require the hormone testosterone for cell growth. Testicles make all the testosterone in men. 2 adrenal glands also create a smaller amount of testosterone.

Enzalutamide is especially the androgen receptor (AR) inhibitor, which would easily enable the threefold inhibition across androgen.

It would be automatically signaling the pathway even without creating the AR agonist activity.

Before taking the medication, it is quite essential to know how long does enzalutamide work for.

Enzalutamide especially inhibits the androgen binding with receptors, interacts with chromosomal DNA, and even makes androgen receptor nuclear translocation.

These would automatically up-regulate Oncogenes with extensively 1,2 Enzalutamide binding AR to 5 to 8-fold affinity.

Normally, the first-generation Antiandrogens like Bicalutamide and 2-3 folds would reduce the affinity compared to natural Ligand Dihydrotestosterone.

Molecular docking especially involves Enzalutamide Binding Ligand binding along with the AR inhibitor.

Enzalutamide comes under the class of medications called as Androgen Receptor inhibitors.

These perfectly work with easily blocking effects of androgen, which is a male reproductive hormone.

Check the enzalutamide cost online from Grant pharmacy before buying the medicine, as it can save you money.

The medicine is also a suitable option for stopping the growth and spread of cancer cells.

How to Use Enzalutamide?

Enzalutamide is available in the form of Capsules or Tablets. The medicine needs to be taken orally with or without food.

You need to consult the doctor to get the enzalutamide dosage prescription before taking the medicine.

Enzalutamide Tablet needs to be taken only once a day. Taking the dosage exactly at the same time every day is quite an efficient option for getting the best result.

Swallow enzalutamide 40 mg as whole and you must not crush or chew the Tablet. You must not divide or dissolve the Tablet for consumption.

You need to take the medication until the doctor recommends it to get the full effect.

Patient-Centered Care at Grant Pharmacy

At Grant Pharmacy, we are committed to providing patient-centered care to individuals undergoing treatment with Enzalutamide. Our team of pharmacists is dedicated to supporting patients every step of the way, from medication management to emotional support and encouragement.

 

• Missed Dose:

Take the Enzalutamide medicine as soon as you remember the dosage. Whether it is time for the next dosage then you need to skip the missed dose and go back on the regular schedule.

You must not be taking the missed dose along with the present dosage. Overdose could be causing various side effects.

• Overdose:

Whether you have accidentally overdosed on the medicine, then you need to seek emergency medical attention immediately. Sometimes, the overdose could be causing the seizure in the body.

Precautions and Warnings:

Before taking the Enzalutamide, it is essential to know about the precautions to be followed. Knowing how long xtandi does stay in your system is essential for getting the full effect.

Normally, Xtandi results in median metastasis-free survival time. Many chemotherapy drugs will be cleared from body waste within 2 days.

Talk to your doctor whether you are taking prescription and nonprescription medications, nutritional supplements or vitamins. The doctor would suggest the right dosage of the medicine to get the full effect.

Talk to your doctor when you are taking the following medicines such as

• Anticoagulants like Warfarin (Coumadin, Jantoven)
• Carbamazepine (Carbatrol, Equetro, Tegretol, Others)
• Ergotamine (Migergot, Cafergot)
• Clopidogrel (Plavix)
• Cyclosporine (Gengraf, Neoral, Sandimmune)
• Dihydroergotamine (D.H.E. 45, Migranal)
• Fentanyl (Actiq, Duragesic, Fentora, Subsys, Others)
• Omeprazole (Prilosec)
• Itraconazole (Onmel, Sporanox)
• Gemfibrozil (Lopid)
• Midazolam
• Phenytoin (Dilantin, Phenytek)
• Rifabutin (Mycobutin, In Talicia)
• Rifampin (Rimactane, In Rifamate, In Rifater)
• Pimozide (Orap)
• Sirolimus (Rapamune)
• Rifapentine (Priftin)

Talk to your doctor when you are taking the herbal products for St. John's Wort or others.

Talk to your doctor when you have had surgery, such as dental surgery, and have been taking the enzalutamide.

Whether you like to know ‘how much does xtandi cost,’ then you can find better options for purchasing Grant online Pharmacy.

Talk to your doctor when you have been taking the medication for various treatments or have a medical history of

• High blood pressure
• Seizures
• Risk factors for seizures (Brain Injury, Stroke and Brain Tumor)
• Heart Disease (such as angina/chest pain, heart attack),
• High Cholesterol or Fats (Triglycerides)
• Diabetes
• Falls
• Broken bones

Side Effects of Enzalutamide:

Taking the Enzalutamide medicine also involves some side effects for the first time. Sometimes, these common and mild enzalutamide side effects could be decreasing over time. Below are some of the signs of an allergic reaction to enzalutamide, such as

• Difficult breathing
• Swelling of your face and tongue
• Hives
• Dizziness, spinning sensation
• Seizure (black-out or convulsions);
• Increased Blood Pressure
• Heart problems
• Red or pink urine
• Constipation, Diarrhoea
• Lung infection

Whether you are facing any of these side effects after taking the Enzalutamide then you need to call the doctor immediately.

Storage:

Store the Enzalutamide tablets at the temperature between 68°F to 77°F or 20°C to 25°C

Keep Enzalutamide tablets dry

Keep the medicine in a tightly closed container

Interactions:

Normally, Drug Interaction could change the effectiveness of the medication in the body. These could be leading to risky side effects, so it is best to check the drug interaction level.

Enzalutamide also interacts with certain drugs. Talk to your doctor about whether you are taking the medicine for various health issues.

You must not start or stop the dosage of Enzalutamide without consulting the doctor. Below is the list of the medicines that Enzalutamide interacts with

• John's Wort - herb inducing CYP3A4 Metabolism of enzalutamide
• Seizure medications (phenobarbital, phenytoin)
• 1,2-Benzodiazepine (serum concentration of 1,2-Benzodiazepine decreased if combined with Enzalutamide)
• Abatacept
• Abacavir (may decrease the excretion rate of Enzalutamide)
• Abametapir (Serum concentration of Enzalutamide increased if combined with Abametapir)
• Abemaciclib (Serum concentration of Abemaciclib decreased if combined with Enzalutamide)
• Ergot Alkaloids (Dihydroergotamine, Ergotamine)
• Pimozide
• Sirolimus
• Voriconazole
• Tacrolimus
• Suvorexant
• Asunaprevir
• Cobicistat

At Grant Pharmacy, we are dedicated to providing comprehensive support and personalized care to individuals undergoing treatment with Enzalutamide.

Frequently Asked Questions about Enzalutamide (FAQs)

Is Enzalutamide A Chemotherapy Treatment?

No, Enzalutamide is not involved with chemotherapy, but it is used for treating cancer cells. These are hormone therapy that works on preventing the growth and spread of prostate cancer cells.

What Is The Function Of Enzalutamide Medicine?

Enzalutamide has the androgen receptor blocker (inhibitor), which blocks testosterone from reaching the Prostate cancer cells. Enzalutamide can also slow the growth of cancer cells, and it could automatically shrink them.

How Long Can I Take Enzalutamide?

Taking the enzalutamide for a longer time could be controlling the cancer cells. Consult with the doctor about the prescription to get the full effect.

When Is The Best Time To Take Enzalutamide?

The patient needs to take Enzalutamide at the same time each day. It is important to swallow the Tablet or capsule as a whole, with or even without food. Whether you are having hormone therapy before taking this medicine, then you can continue it.

Does Enzalutamide Affect Memory?

There are reports stating the high dosage of enzalutamide can lead to memory impairment and anxiety. But these do not deal with the abiraterone acetate.