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Macitentan (Opsutan)

Macitentan Tablets 10mg (Opsutan) is a prescription drug useful for treating pulmonary arterial hypertension or high Blood Pressure in the vessels.
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Macitentan (Opsutan) 10mg

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What Is Macitentan Tablets 10mg (Opsutan)?

Macitentan Tablets 10mg (Opsutan) is a prescription drug useful for treating pulmonary arterial hypertension or high Blood Pressure in the vessels.

These blood vessels carry the blood from the heart to the lungs.

These are significant options for helping to delay the disease progression and even improve quality of life.

The opsutan tablet is available with a combination of various medicines.

These medications need to be taken with or even without food.

 Opsutan medicine needs to be used regularly to get full benefit.

 Doctors would suggest the appropriate dosage for improving the symptoms.

Normally, opsutan 10 mg contains Macitentan, and this belongs to the Group of Medicines called the Endothelin Receptor Antagonists.

These medicines are used with many other medicines for treating pulmonary hypertension in adults.

It is a condition which occurs commonly due to the higher high blood pressure in the pulmonary arteries or blood vessels carrying the blood from the heart to the lungs.

 Normally, the Macitentan Tablets 10mg (Opsutan) will not be given to patients who are allergic to the Macitentan or Soya.

The medication is also not prescribed for patients who have higher levels of Liver enzymes in the blood.

How Does Macitentan Tablets 10mg (Opsutan) Work?

Macitentan Tablets 10mg is widely called as Endothelin Receptor Blocker. The medication works by blocking the action of endothelin.

The endothelin is a substance that causes the blood vessels carrying the blood to the lungs to get narrow or constrict.

Narrowing of the blood vessels would increase pressure in the blood vessels of the lungs.

Taking the macitentan helps the patient to relax blood vessels along with easily increasing the supply of blood for the lungs. 

Pulmonary arterial hypertension or PAH can cause shortness of tiredness, dizziness, breath, swelling in ankles and legs and chest pain.

 Pulmonary arterial hypertension can be caused by thickening of the walls of arteries.

The arteries supply the lungs with the blood, so the PAH causes the blood vessels to narrow. Taking the macitentan 10 mg helps to relax the blood vessels easily.

These are also helpful for lowering the blood pressure in the arteries of the lungs.

It is easier for the patients to carry out their daily activities more effectively and feel less dizzy.

The Macitentan Tablets 10mg (Opsutan) works with blocking the action of the endothelin hormone.

The endothelin hormone is a chemical causing vasoconstriction, and this leads to the relaxing and widening of the blood vessel walls.

 It results in a reduced range of blood pressure in blood vessels.

Lowering blood pressure automatically can be useful for reducing dizziness and tiredness.

 Macitentan Tablets 10mg is a spectacular option for treating pulmonary hypertension in the affected individuals.

Taking the exact dose is essential for getting the complete effect of the medicine to work in the body.

How To Use Macitentan Tablets 10mg (Opsutan)?

Taking the Macitentan Tablets 10mg (Opsutan in the accurate dose prescribed by the doctor is important.

Consult the doctor to get the macitentan dosage and duration of the medicine.

Do not crush, chew, or break the medicine.

Swallow the macitentan tablets 10mg (Opsutan) as whole with or without food.

 Take the medicine at a fixed time every day to get the full effect. Swallow the medicine with a glass of water.

Missed Dose:

Whether you have missed a dose of Macitentan Tablets 10mg then you need to take the medicine as soon as you remember it.

When it is almost time for the next dosage then you can skip the missed dose and continue with the regular schedule. Do not double-dose the Opsutan medicine, as it could lead to serious side effects.


Whether you or anyone else have taken more amounts of the Macitentan Tablets 10mg accidentally, then it is important to consult a doctor immediately. Overdosing could cause some side effects, such as headache, nausea, vomiting and many others.

Precautions And Warnings:

  • Pregnancy:

Macitentan Tablets 10mg (Opsutan) are not recommended for use by women during pregnancy or planning for pregnancy. 

Women of childbearing potential must use contraceptive measures. Consult the doctor to get the prescription if accidental pregnancy occurs when taking the medicine.

  • Breastfeeding:

Normally, the Macitentan Tablets 10mg is not recommended for use in breastfeeding women. These could be causing the side effects on the child as the medicine could pass through the breast milk. Immediately consult the doctor before taking the opsutan tablet.

  • Driving And Using Machines:

Doctors recommend not operating machines or driving when you are taking the macitentan tablets 10 mg (Opsutan).

Some patients could feel the headache or even low blood pressure when taking the medication.

  • Liver:

Doctors do not recommend the Doctors Macitentan Tablets 10mg (Opsutan) for patients with liver diseases. These are also not prescribed for patients who are tested with higher levels of Liver enzymes in the blood. Please consult the doctor before taking the medication for pulmonary arterial hypertension.

  • Kidney:

Patients with kidney problems must take the Macitentan Tablets 10mg (Opsutan) with extreme caution. Please consult the doctor before taking the medication.

  • Allergy:

Whether you are allergic to the Macitentan, soya, or even other ingredients used in this medicine, then it is better to avoid taking the medicine.

  • Lungs:

Macitentan Tablets 10mg (Opsutan) need to be taken with extreme caution when you have a history of lung diseases like Pulmonary Veno-Occlusive Disease or Obstruction of the lung vein. Please consult your doctor before taking the Macitentan Tablets 10mg.

  • Use In Pediatrics:

Opsutan Tablets are not recommended for usage in adolescents or children. Please consult the doctor before taking the Opsutan tablet for pulmonary arterial hypertension.

While taking the Macitentan Tablets 10mg (Opsutan), it is essential to take certain precautions and warnings.

Maintain your diet with vegetables, fruits, omega-3-rich foods, lean protein sources, whole grains, legumes and many more.

Keep the body weights under control using a BMI of 19.5 to 24.9.

Include heart-healthy omega-3 fatty acids-enabled food in the diet.

Use lower-fat cooking oil such as soybean oil, coconut oil, canola oil, and olive oil. These would be automatically lowering the elevated blood pressure.

It is best to avoid taking chronic stress as these could raise blood pressure.

Spend more time with loved ones, and you need to practice mindfulness techniques.

Do not consume salt more than 2,300 mg each day in the food.

Avoid taking the alcohol or smoking. Save more money on the purchase with the lowest macitentan price online via Grant Pharmacy

Patient Support Programs:

Grant Pharmacy provides comprehensive patient support programs, offering assistance with medication management and access to resources.

Side Effects Of Macitentan Tablets 10mg (Opsutan):

Before taking the Macitentan Tablets 10mg (Opsutan), it is best to know about the side effects involved with the medication. Some of the common and rare macitentan side effects are listed below.


  • Anaemia or reduced hemoglobin
  • Edema (swelling in arms and feet)
  • Bronchitis
  • Influenza (flu)
  • Nasopharyngitis (inflammation in throat and nasal passages)
  • Urinary tract infection


  • Signs of impaired liver function - vomiting, fever, stomach pain and nausea
  • Signs of allergic reaction - swelling on face, lips, eyes, tongue/throat, itching,

Avoid taking Macitentan Tablets 10mg (Opsutan) when you are facing these side effects. Consult your doctor immediately when you experience these side effects


Store Macitentan Tablets 10mg in a cool and dry place

Keep the medicine away from sunlight

Global Accessibility:

Grant Pharmacy offers worldwide shipping, making Macitentan Tablets 10mg accessible to individuals seeking effective PAH treatment globally.


Drug-Drug Interactions:

Macitentan Tablets 10mg (Opsutan) medicine can interact with certain drugs, which could cause side effects. Below are some of the drug interactions with Opsutan listed

  • Antibiotics - Telithromycin, Ciprofloxacin, Erythromycin, Rifampicin, Clarithromycin
  • Medicine to treat epilepsy and depression - Carbamazepine
  • Medicines to treat depression - Nefazodone
  • Medicines to treat HIV infections - Ritonavir, Saquinavir
  • Medicines to treat seizures - Phenytoin
  • Herbal Medicines to treat depression - St. John’s Wort
  • Medicines to treat and prevent organ rejection after transplant - Cyclosporine

Drug-Food Interaction:

Avoid consuming Alcohol as it can increase the side effects of the Opsutan Tablet

Avoid taking Piperine when using Macitentan Tablets 10mg

Frequently asked questions about Macitentan Tablets 10mg (Opsutan) (FAQs):

What Are Macitentan Tablets 10mg (Opsutan) Used For?

Macitentan Tablets 10mg (Opsutan) is used for treating pulmonary arterial hypertension, a condition that occurs due to high blood pressure in the pulmonary arteries.

How Macitentan Tablets 10mg Should Be Taken?

Take Macitentan Tablets 10mg as advised by a physician. You must Swallow the Tablet with a glass of water, and you must not crush or chew the medicine.

What Are The Common Side Effects Of Taking Macitentan Tablets?

Common side effects of taking Macitentan Tablets are anaemia, urinary tract infection, headache, and more. Consult a doctor when you are having the symptoms.

How Macitentan Tablets Works?

Macitentan Tablets work by blocking the action of Endothelin Hormone, which is a chemical causing vasoconstriction that leads to the relaxation of the blood vessel wall

Can Macitentan Tablets 10mg (Opsutan) Be Used In Pregnant Women?

No, the Macitentan Tablets 10mg is not recommended for pregnant women or breastfeeding. Women of childbearing potential need to use contraceptive measures for the medication.

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