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Viagra Super Force

Viagra Super Force is classified as an oral medication for male sexual dysfunction.
ED with Premature Ejaculation
Ajanta Pharmaceuticals
Sildenafil Citrate and Dapoxetine

Viagra Super Force 160 mg

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Usage

Drug Information

Viagra Super Force is classified as an oral medication for male sexual dysfunction. It not only acts as preventive means but also as erectile disorders treatment. It was particularly appreciated by men who cannot perform long-lasting sexual intercourse.

Each pill contains 100 mg of Sildenafil and 60 mg of Dapoxetine. The drug acts during 4 – 5 hours. The effect can be expected within 40 minutes after administration. Pills have a bitter taste. It is forbidden to take medication with alcohol.

Viagra Super Force can be called «Super-Viagra». The drug is an excellent choice for those who want to extend sexual intercourse duration and increase potency.

Pharmacological

Viagra Super Force Sildenafil is a powerful selective cyclic guanosine monophosphate (cGMP) – specific phosphodiesterase type 5 (PDE-5) – inhibitor.

Mechanism of Action

Physiological erection mechanism is directly connected to the reaction, during which, at sexual stimulation, nitric oxide (NO) in cavernous bodies is released. Reaction stimulates cGMP level increase followed by blood flow stimulation and cavernous bodies smooth muscle relaxation.

Active ingredient of Viagra Super Force has an indirect influence on the process, not acting directly on the cavernous body, it only enhances nitric oxide effect by means of inhibiting PDE-5, which leads to cGMP breakdown.

Sildenafil is selective against PDE-5 in vitro, its activity against PDE-5 surpasses activity against other known phosphodiesterase isoenzymes: PDE-6 – 10 times; PDE-1 – more than 80 times; PDE-2, PDE-4, PDE-7-PDE-11 – more than 700 times. Sildenafil 4000 times more selective against PDE-5 compared to PDE-3, it is important because PDE-3 is one of the main enzymes that are involved in cardiac contractility regulation.

To achieve Sildenafil effectiveness sexual stimulation is required.

Pharmacokinetics

Pharmacokinetics in recommended dosage range is linear.

Elderly patients

Patients in the age group older than 65 years Sildenafil clearance is reduced and its free concentration in blood plasma is about 40% higher than in patients of 18 – 45 years old. Patient’s age has no significant clinical impact on side effects incidence.

Renal function disorders

At mild (creatinine clearance (CC) is 50-80 ml/min) or moderately severe (creatinine clearance is 30-49 ml/min) renal insufficiency, pharmacokinetics, in case of drug single dose 50 mg, will not change. If the patient has severe renal insufficiency.

At patients with cirrhosis (stages A and B, according to Child-Pugh classification) Sildenafil clearance is reduced, there is AUC (84%) and Cmax (47%) indicators increase in comparison with those of patients of the same age group, but with normal hepatic function. Sildenafil pharmacokinetics in patients with severe hepatic function disorders (stage C according to Child-Pugh classification) was not studied.

Indications
Viagra Super Force is indicated for erectile dysfunction treatment – inability to achieve or maintain penis erection sufficient for satisfactory sexual intercourse. Sildenafil efficacy of is achievable only with further sexual stimulation.

Dosage
The initial dosage of the product ranges from 25 to 100 mg a day. Experts recommend taking the drug 1 hours before planned sexual intercourse. It can be said Viagra Super Force ED Drugthat this means does not hurt the body, which implies it can be taken independently, without doctor’s prescription, you just have to read instructions and know all details and nuances, and then health problems will not occur.

Effect on the Body
We have already mentioned above, active ingredients of medication are Sildenafil citrate (100 mg) and Dapoxetine (60 mg). Sildenafil effect is characterized by penile muscles’ relaxation, thereby increasing blood flow to the penis. Dapoxetine slows down ejaculation process, it allows you to avoid premature ejaculation.


We only ship medications which are approved by FDA, Also please consult your doctor to make a full decision on what medication to take.

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